贾光

职业有害因素致病机制及防治研究。

1、国家自然科学基金委员会面上项目（82473600）人工智能+糖脂代谢系统解析铬酸盐致肺组织损伤、衰老及预警策略研究, 2025-01-01至2028-12-31，主持。

2、国家自然科学基金委员会面上项目（82273603）间充质干细胞可塑性驱动的铬酸盐肺损伤与修复机制研究, 2023-01-01至2026-12-31，主持。

3、国家自然科学基金联合基金重点项目（U2004202）基于免疫调节的铬酸盐职业暴露早期遗传损伤及修复机制研究, 2021-01至2024-12，主持。

4、国家自然科学基金面上项目（81872598）基于联合组学技术的铬酸盐职业接触致呼吸系统损伤及修复机制研究，2019/01-2022/12，主持。

5、国家自然科学基金重大研究计划（91743114）大气颗粒物（PM2.5）及有效组分对大鼠遗传物质损伤及修复的影响，2018/01-2020/12，主持。

6、国家自然科学基金面上项目（81573118）基因环境交互作用对铬酸盐所致遗传损伤的机制研究，2016/01-2019/12，主持。

7、国家自然科学基金面上项目（81273043），基于分子暴露组学的铬致癌早期效应研究，2012-01-01至2016-12-31，主持。

8、国家自然科学基金面上项目（81072281），职业接触铬盐对体内多元素影响及机制研究，2010-01-01至2013-12-31，主持。

9、国家自然科学基金面上项目（30771787），不同尺寸纳米级二氧化钛对生产者健康效应的初步研究，2008-01-01至2010-12-31，主持。

10、国家自然科学基金面上项目（30571550），铬盐接触者遗传易感性的研究，2006-01-01至2008-12-31，主持。

1. Zekang Su, Yali Zhang, Shiyi Hon, Qiaojian Zhang, Zhiqiang Ji, Guiping Hu, Xiaojun Zhu, Fang Yuan, Shanfa Yu, Tianchen Wang, Li Wang, Guang Jia*. Immune Regulation Patterns in Response to Environmental Pollutant Chromate Exposure-Related Genetic Damage: A Cross-Sectional Study Applying Machine Learning Methods [J]. Environ Sci Technol, 2024, DOI10.1021/acs.est.4c00433.

2. Guiping Hu, Changmao Long, Lihua Hu, Yali Zhang, Shiyi Hong, Qiaojian Zhang, Pai Zheng, Zekang Su, Jiayu Xu, Li Wang, Xiaoying Gao, Xiaojun Zhu, Fang Yuan, Tiancheng Wang, Shanfa Yu, Guang Jia*. Blood chromium exposure, immune inflammation and genetic damage: Exploring associations and mediation effects in chromate exposed population [J]. J Hazard Mater, 2022, 425: 127769.

3. Zhangjian Chen, Di Zhou, Shuo Han, Shupei Zhou, Gaung Jia*. Hepatotoxicity and the role of the gut-liver axis in rats after oral administration of titanium dioxide nanoparticles [J]. Part Fibre Toxicol, 2019, 16(1): 48.

4. Lin Zhao, Yifang Zhu, Zhangjian Chen, Huadong Xu, Jingwen Zhou, Shichuan Tang, Zhizhen Xu, Fanling Kong, Xinwei Li, Yifei Zhang, Xianzuo Li, Ji Zhang, Guang Jia*. Cardiopulmonary effects induced by occupational exposure to titanium dioxide nanoparticles [J]. Nanotoxicology, 2018, 12(2): 169-184.

5. Qian Qin, Li Ping, Wang Tiancheng, Zhang Ji, Yu Shanfa, Chen Tian, Yan Lei, Song Yanshuang, Liu Xiang, Gu Yongen, Wang Yun, Jia Guang*. Alteration of Th1/Th2/Th17 cytokine profile and humoral immune responses associated with chromate exposure [J]. Occup Environ Med, 2013, 70(10):697-702.

6. Yun Wang, Zhangjian Chen, Te Ba, Ji Pu, Tian Chen, Yanshuang Song, Yongen Gu, Qin Qian, Yingying Xu, Kun Xiang, Haifang Wang, Jia Guang*. Susceptibility of Young and Adult Rats to the Oral Toxicity of Titanium DioxideNanoparticles [J]. Small. 2013, 9(9-10): 1742-52.

7. Song Yanshuang, Zhang Ji, Yu Shanfa, Wang Tiancheng, Cui Xxiaoxing, Du Xianmei, Jia Guang*. Effects of chronic chromium(vi) exposure on blood element homeostasis: an epidemiological study [J]. Metallomics, 2012, 4(5):463-72.

8. Tiancheng Wang, Yanshaung Song, Haifang Wang, Ji Zhang, Shanfa Yu, Yongen Gu, Tian Chen, Yun Wang, Huiqi Shen, Guang Jia*. Oxidative DNA damage and global DNA hypomethylation are related to folate deficiency in chromate manufacturing workers [J]. J Hazard Mater, 2012, 213-214: 440-6.

9. Zhen Shen, Qian Qin, Jia Guang*, Zhang Ji, Chen Chunying, Wei Yongjie. A panel study for cardiopulmonary effects produced by occupational exposure to inhalable titanium dioxide. J Occup Environ Med, 2012, 54(11):1389-94.

10. Guang Jia, Haifang Wang, Lei Yan, Xiang Wang, Rongjuan Pei, Tao Yan, Yuliang Zhao, Xinbiao Guo. Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene [J]. Environ Sci Technol, 2005, 39 (5): 1378-1383.